Imidacloprid ndi Moxidectin Spot-on Solutions (za Amphaka)

【Zosakaniza】

Imidacloprid, Moxidectin

【Maonekedwe】

Madzi achikasu mpaka bulauni.

Pharmacological zochita:Antiparasite mankhwala. Pharmacodynamics:Imidacloprid ndi m'badwo watsopano wa mankhwala ophera chikonga a chlorinated. Ili ndi kuyanjana kwakukulu kwa postsynaptic nicotinic acetylcholine receptors m'katikati mwa mitsempha ya tizilombo, ndipo imatha kulepheretsa ntchito ya acetylcholine, zomwe zimapangitsa kuti tiziromboti tizifa ziwalo ndi imfa. Ndiwothandiza polimbana ndi utitiri wamkulu ndi utitiri wachichepere pa magawo osiyanasiyana, komanso umapha utitiri wachichepere m'chilengedwe.

Njira ya zochita za moxidectin ndi yofanana ndi ya abamectin ndi ivermectin, ndipo imakhala ndi zotsatira zabwino pamagulu amkati ndi akunja, makamaka nematodes ndi arthropods. Kutulutsidwa kwa butyric acid (GABA) kumawonjezera mphamvu yake yomangiriza ku postsynaptic receptor, ndipo njira ya chloride imatsegulidwa. Moxidectin imakhalanso ndi selectivity ndi kuyanjana kwakukulu kwa glutamate mediated chloride ion channels, potero imasokoneza mauthenga a neuromuscular, kumasuka ndi kupumitsa tizilombo toyambitsa matenda, zomwe zimayambitsa imfa ya tizilombo toyambitsa matenda.

Ma interneurons olepheretsa ndi ma neuromus osangalatsa a ma nematode ndi malo ake ochitirapo kanthu, pomwe mu arthropods ndi gawo la neuromuscular. Kuphatikiza kwa ziwirizi kumakhala ndi zotsatira za synergistic. Pharmacokinet ics: Pambuyo pa makonzedwe oyamba, imidacloprid idagawidwa mwachangu ku thupi la mphaka tsiku lomwelo, ndipo idakhalabe pathupi pa nthawi ya makonzedwe atatha masiku 1-2 pambuyo pa makonzedwe, plasma ndende ya moxidectin mu amphaka imafika pamlingo wapamwamba kwambiri. ,ndipo imagawidwa m'thupi lonse mkati mwa mwezi umodzi ndipo imapangidwa pang'onopang'ono ndikutulutsidwa.

【Kagwiritsidwe ndi mlingo】

Izi zikusonyeza kupewa ndi kuchizamu vivondimu vitro matenda parasitic amphaka. Izi zimasonyezedwa pofuna kupewa ndi kuchiza matenda a utitiri(Ctenocephalus felis), kuchiza matenda a nthata m'makutu(Pruritus auris), chithandizo cha matenda a m'mimba nematode (akuluakulu, akuluakulu osakhwima ndi mphutsi za L4Matenda a ToxocarriandiHamnostoma tubuloides), kupewa matenda a mtima filariasis (L3 ndi L4 siteji achinyamata a heartworms). Ndipo amatha kuthandizira pochiza matupi awo sagwirizana dermatitis chifukwa cha utitiri.

【Kagwiritsidwe ndi mlingo】

Kugwiritsa ntchito kunja. Mlingo umodzi, mphaka pa 1kg kulemera kwa thupi, 10mg imidacloprid 1mg moxidectin, wofanana 0.1ml mankhwala. Pa nthawi ya prophylaxis kapena chithandizo, tikulimbikitsidwa kupereka kamodzi pamwezi. Pofuna kupewa kunyambita, gwiritsani ntchito khungu kokha kumbuyo kwa mutu wa mphaka ndi khosi.

【Zotsatira】

(1) Muzochitika payekha, mankhwalawa angayambitse kusamvana komweko, kuchititsa kuyabwa kwakanthawi, kumamatira kwatsitsi, erythema kapena vomiting. Zizindikirozi zimatha popanda chithandizo.

(2) Pambuyo poyang'anira, ngati chiweto chikunyambita malo otsogolera, zizindikiro zowonongeka za ubongo zimatha kuwoneka nthawi zina, monga chisangalalo, kunjenjemera, zizindikiro za maso (ana aang'ono, pupillary reflexes, ndi nystagmus), kupuma kwachilendo, kutulutsa malovu, ndi Zizindikiro monga kusanza. ;nthawi zina kusintha kwamakhalidwe kwapang'onopang'ono monga kusafuna kuchita masewera olimbitsa thupi, chisangalalo, komanso kusowa chidwi.

【Kusamalitsa】

(1) Osagwiritsa ntchito ana amphaka osakwana milungu 9 yakubadwa. Osagwiritsa ntchito amphaka omwe sakugwirizana ndi mankhwalawa. Agalu apakati ndi oyamwitsa ayenera kutsatira malangizo a Chowona Zanyama asanagwiritse ntchito.

(2) Amphaka osakwana 1kg ayenera kutsatira malangizo a Chowona Zanyama akamagwiritsa ntchito mankhwalawa.

(3)Ndikoyenera kupewa Collies, Old English Sheepdogs ndi mitundu yofananira kunyambita mankhwalawa pakamwa.

(4) Amphaka ndi amphaka omwe ali ndi thupi lofooka ayenera kutsatira malangizo a veterinarian akamagwiritsa ntchito.

(5) Izi siziyenera kugwiritsidwa ntchito kwa agalu.

(6)Panthawi yogwiritsira ntchito mankhwalawa, musalole kuti mankhwala omwe ali mu chubu la mankhwala akhudze maso ndi pakamwa pa nyama yomwe ikugwiritsidwa ntchito kapena nyama zina.Pewani kuti nyama zomwe zatha mankhwala zisamanyambire. Osakhudza kapena kudula tsitsi mpaka mankhwala atauma.

(7) Nthawi zina 1 kapena 2 kuwonetseredwa kwa amphaka kumadzi pa nthawi ya utsogoleri sikudzakhudza kwambiri mphamvu ya mankhwalawa. Komabe, amphaka omwe amasamba pafupipafupi ndi shampu kapena zoviikidwa m'madzi amatha kusokoneza mphamvu ya mankhwalawa.

(8)Atetezeni ana kuti asakumane ndi mankhwalawa.

(9) Osasunga pamwamba pa 30 ℃, ndipo musagwiritse ntchito kupyola tsiku lotha ntchito.

(10)Anthu omwe ali ndi matupi awo sagwirizana ndi mankhwalawa sayenera kupereka.

(11) Popereka mankhwalawa, wogwiritsa ntchito ayenera kupewa kukhudzana ndi khungu, maso ndi pakamwa pa mankhwalawa, osadya, kumwa kapena kusuta; pambuyo pa utsogoleri, manja ayenera kusambitsidwa. Ngati izo

Ikathira pakhungu mwangozi, isambitseni ndi sopo ndi madzi nthawi yomweyo; ngati ilowa m'maso mwangozi, ichapani ndi madzi nthawi yomweyo. Ngati zizindikiro sizikuyenda bwino, chonde funsani dokotala

malangizo.

(12)Pakali pano, palibe mankhwala enieni opulumutsira mankhwalawa; ngati atamezedwa molakwika, makala opangidwa m'kamwa angathandize kuchotsa poizoni.

(13) Zosungunulira zomwe zili muzinthuzi zimatha kuyipitsa zinthu monga zikopa, nsalu, pulasitiki, ndi malo opaka utoto. Malo otsogolera asanayambe kuuma, letsani zipangizozi kuti zisagwirizane ndi malo otsogolera.

(14)Musalole kuti mankhwalawa alowe m'madzi apamwamba.

(15)Mankhwala osagwiritsidwa ntchito ndi zopakira ziyenera kutayidwa mopanda vuto malinga ndi zofunikira zakumaloko.

【Nthawi yochotsa】Palibe.

【Zofotokozera】

(1)0.4ml:Imidacloprid 40mg+Moxidectin 4mg

(2)0.8ml:Imidacloprid 80mg +Moxidectin 8mg

【Posungira】Zosindikizidwa, zosungidwa kutentha.

【Alumali moyo】3 zaka.