Imidacloprid ndi Moxidectin Spot-on Solutions (za Agalu)

【Chofunika Kwambiri】

Imidacloprid, Moxidectin

【Maonekedwe】

Madzi achikasu mpaka bulauni.

【Pzochita za harmonic】

Antiparasite mankhwala.

Pharmacodynamics:Imidacloprid ndi m'badwo watsopano wa mankhwala ophera chikonga a chlorinated. Lili ndi kuyanjana kwakukulu kwa postsynaptic nicotinic acetylcholine zolandilira m'katikati mwa mitsempha ya tizilombo, ndipo zimatha kulepheretsa ntchito ya acetylcholine, zomwe zimapangitsa kuti tiziromboti tife ziwalo ndi imfa. Ndiwothandiza polimbana ndi utitiri wamkulu ndi utitiri wachichepere pa magawo osiyanasiyana, komanso umakhudza kwambiri utitiri wachichepere m'chilengedwe. Limagwirira wa zochita za moxidectin ndi ofanana ndi abamectin ndi ivermectin, ndipo ali wabwino kiling zotsatira za mkati ndi kunja majeremusi, makamaka nematodes ndi arthropods. Kutulutsidwa kwa butyric acid (GABA) kumawonjezera mphamvu yake yomangirira ku postsynaptic receptor, ndipo njira ya chloride imatsegulidwa. Moxidectin imakhalanso ndi kusankha komanso kuyanjana kwakukulu kwa njira za ion glutamate-mediated chloride ion, potero zimasokoneza kufalikira kwa chizindikiro cha neuromuscular, kupumula ndi kupumitsa tizilombo toyambitsa matenda, zomwe zimayambitsa imfa ya tizilombo toyambitsa matenda. Ma interneurons oletsa ndi ma neuromuscular motor mu nematodes ndi malo ake ochitirapo kanthu, pomwe mu arthropods ndi neuromuscular junction. Kuphatikiza kwa ziwirizi kumakhala ndi zotsatira za synergistic.

Pharmacokinetics:Pambuyo pa utsogoleri woyamba, imidacloprid idagawidwa mwachangu ku thupi la galu tsiku lomwelo, ndipo idakhalabe pathupi pa nthawi ya makonzedwe atatha masiku 4-9 pambuyo pa makonzedwe, plasma ndende ya moxidectin mwa agalu imafika pamlingo wapamwamba kwambiri. imagawidwa m'thupi lonse mkati mwa mwezi umodzi ndipo imapangidwa pang'onopang'ono ndikutulutsidwa.

【Zizindikiro】
Pakuti kupewa ndi kuchiza mkati ndi kunja parasitic matenda agalu. Kupewa ndi kuchiza matenda a utitiri (Ctenocephalic canis), chithandizo cha nsabwe (Catonicus canis), kuchiza nsabwe za m'makutu (ltchy otica), canine sarcoids (scabies mites), ndi demodicosis (Demodex canis), pochiza Angiostrongylus ndi matenda a m'mimba nematode (akuluakulu, aduts osakhwima ndi L4mphutsi za Toxocara canis, Ancylostoma canis, ndi Ancylocephalus mphutsi;akuluakulu a Toxocara lionis ndi Trichocephala vixensis). Ndipo angagwiritsidwe ntchito ngati adjuvant mankhwala a Matupi dermatitis chifukwa cha utitiri.

【Kagwiritsidwe ndi mlingo】
Kugwiritsa ntchito kunja, dontho izi pakhungu kuchokera kumbuyo kwa galu pakati pa mapewa awiri mpaka matako, ndikuwagawa m'malo 3-4. Mlingo umodzi, wa agalu, pa 1kg ya kulemera kwa thupi, 10mg ya imidacloprid ndi 2.5mg ya moxidectin, yofanana ndi 0.1ml ya mankhwalawa. Pa nthawi ya prophylaxis ortreatment, tikulimbikitsidwa kupereka kamodzi pamwezi. Kuletsa agalu kunyambita.

【Zotsatira zake】

(1) Muzochitika payekha, mankhwalawa angayambitse kusagwirizana ndi komweko, kuchititsa kuyabwa kwakanthawi, kumamatira tsitsi, erythema kapena kusanza. Zizindikirozi zimatha popanda chithandizo.

(2) Pambuyo poyang'anira, ngati chiweto chikunyambita malo otsogolera, zizindikiro za ubongo zimatha kuwoneka nthawi zina, monga chisangalalo, kunjenjemera, zizindikiro za maso (ana aang'ono, pupillary reflexes, ndi nystagmus), kupuma kwachilendo, kutulutsa malovu, ndi Zizindikiro monga kusanza. ; nthawi zina kusintha kwamakhalidwe kwanthawi yayitali monga kusafuna kuchita masewera olimbitsa thupi, chisangalalo, komanso kusowa kwa njala kumachitika.

【Kusamalitsa】

(1) Osagwiritsa ntchito ana agalu osakwana milungu 7. Agalu omwe sali osagwirizana ndi mankhwalawa asamagwiritse ntchito. Agalu apakati ndi oyamwitsa ayenera kutsatira malangizo a Chowona Zanyama asanagwiritse ntchito.

(2) Agalu osakwana 1kg ayenera kutsatira malangizo a Chowona Zanyama akamagwiritsa ntchito mankhwalawa.

(3) Mankhwalawa ali ndi moxidectin(macrocyclic lactone), kotero mukamagwiritsa ntchito mankhwalawa pa collies, agalu akale achingerezi ndi mitundu yofananira, chidwi chapadera chiyenera kuperekedwa kuti aletse agaluwa kunyambita izi.mankhwala pakamwa.

(4)Agalu odwala ndi agalu omwe ali ndi thupi lofooka ayenera kutsatira malangizo a veterinarian akamagwiritsa ntchito.

(5) Izi siziyenera kugwiritsidwa ntchito pa amphaka.

(6)Panthawi yogwiritsira ntchito mankhwalawa, musalole kuti mankhwala omwe ali mu chubu la mankhwala akhudze maso ndi pakamwa pa nyama yomwe ikugwiritsidwa ntchito kapena nyama zina.Pewani kuti nyama zomwe zatha mphamvu zisamanyambirene. Osakhudza kapena kudula tsitsi mpaka mankhwala atauma.

(7) Nthawi zina 1 kapena 2 kuwonetseredwa kwa agalu pamadzi pa nthawi ya utsogoleri sikudzakhudza kwambiri mphamvu ya mankhwalawa. Komabe, kugwiritsa ntchito shampu pafupipafupi posamba kapena kumizidwa m'madzi ndi agalu kumatha kusokoneza mphamvu ya mankhwalawa.

(8)Atetezeni ana kuti asakumane ndi mankhwalawa.

(9) Osasunga kuposa 30℃,ndipo musagwiritse ntchito kupyola tsiku lotha ntchito.

(10)Anthu omwe ali ndi matupi awo sagwirizana ndi mankhwalawa sayenera kupereka.

(11) Popereka mankhwalawa, wogwiritsa ntchito ayenera kupewa kukhudzana ndi khungu, maso ndi pakamwa pa mankhwalawa, osadya, kumwa kapena kusuta; pambuyo pa utsogoleri, manja ayenera kusambitsidwa. Ikathira pakhungu mwangozi, tsukani ndi sopo ndi madzi nthawi yomweyo; ngati ilowa m'maso mwangozi, ichapani ndi madzi nthawi yomweyo.

(12)Pakali pano, palibe mankhwala enieni opulumutsira mankhwalawa; ngati atamezedwa molakwika, makala opangidwa m'kamwa angathandize kuchotsa poizoni.

(13) Zosungunulira zomwe zili muzinthuzi zimatha kuyipitsa zinthu monga zikopa, nsalu, pulasitiki, ndi malo opaka utoto. Malo otsogolera asanayambe kuuma, pewani zinthuzi kuti zisalumikizane ndi malo oyang'anira

(14)Musalole kuti mankhwalawa alowe m'madzi apamwamba.

(15)Mankhwala osagwiritsidwa ntchito ndi zopakira ziyenera kutayidwa mopanda vuto malinga ndi zofunikira zakumaloko.

【Kuchotsa  nthawi】Palibe

【Kufotokozera】

(1)0.4ml:Imidacloprid 40mg +Moxidectin 10mg

(2) 1.0ml:Imidacloprid 100mg+Moxidectin 25mg

(3)2.5ml:Imidacloprid 250mg +Moxidectin 62.5mg

(4) 4.0ml:Imidacloprid 400mg+Moxidectin 100mg

 【Kusungirako】

Zosindikizidwa, zosungidwa kutentha.

【Alumali moyo】

3 zaka